IMMUNOLOGY2026™ Conference Recordings For Attendees-A High-Throughput, Systems-based Neutralizing Antibody Assay Identifies Humoral Features Linked with Compartmentalized Neutralization

A High-Throughput, Systems-based Neutralizing Antibody Assay Identifies Humoral Features Linked with Compartmentalized Neutralization

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Video Summary

The speaker introduced SNAP, a high-throughput, bead-based, Luminex neutralization assay for influenza that avoids live cells, viruses, and endpoint titering. By measuring competition between viral hemagglutinin and sialic acid receptor binding, the assay can run 30–50 targets at once in under a day, using less sample and lower biosafety requirements. In nonhuman primate vaccine studies, SNAP correlated strongly with standard micro-neutralization and HAI assays. It was also much cheaper and more scalable. The team is exploring use in low-resource settings and for novel flu targets beyond traditional HA, including neuraminidase and other antigens.

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Date April 18, 2026 1:30 PM - 1:45 PM

Room 151

Session Technical Innovations for Therapies

Speaker Qixin Wang

Track Technological Innovations in Immunology (TECH)

Year 2026

Keywords

SNAP assay

influenza neutralization

Luminex assay

hemagglutinin binding

vaccine studies

April 18, 2026 1:30 PM - 1:45 PM

151

Technical Innovations for Therapies

Qixin Wang

Technological Innovations in Immunology (TECH)

2026