IMMUNOLOGY2026™ Conference Recordings For Attendees-Role of Periodontitis in Inflammatory Bowel Disease

Role of Periodontitis in Inflammatory Bowel Disease

Video Transcription

Video Summary

Dr. Hemanti Tanwar discussed how periodontitis may contribute to inflammatory bowel disease (IBD) through oral bacteria translocating to a disrupted gut. Using IRF8 knockout mice, her team showed periodontal bone loss, oral pathogens reaching the intestine, and resulting colitis-like inflammation driven by B cells, IgG, and TH17 responses. Treating periodontitis reduced gut inflammation. Human studies also linked IBD with higher periodontitis and oral pathogen burden, suggesting that improving dental health may lower IBD risk by limiting colitogenic bacteria.

Meta Tag

Date April 16, 2026 10:27 AM - 10:42 AM

Room Ballroom

Session Major Symposium B: Microbiome Influence on Epithelial-immune Crosstalk

Speaker Himanshi Tanwar

Track Mucosal And Regional Immunology (MUC)

Year 2026

Keywords

periodontitis

inflammatory bowel disease

oral bacteria

colitis inflammation

dental health

April 16, 2026 10:27 AM - 10:42 AM

Ballroom

Major Symposium B: Microbiome Influence on Epithelial-immune Crosstalk

Himanshi Tanwar

Mucosal And Regional Immunology (MUC)

2026